Enhanced brain distribution of modified aspartoacylase
نویسندگان
چکیده
منابع مشابه
Bimodal occurrence of aspartoacylase in myelin and cytosol of brain.
The growing use of N-acetylaspartate as an indicator of neuronal viability has fostered interest in the biological function(s) of this unusual amino acid derivative. In considering the various physiological roles that have been proposed for this relatively abundant molecule one is obliged to take into account its unusual metabolic compartmentalization, according to which synthesis and storage o...
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Several characterizations of a New Modified Weibull distribution, introduced by Doostmoradi et al. (2014), are presented. These characterizations are based on: (i) truncated moment of a function of the random variable (ii) the hazard function (iii) a single function of the random variable (iv) truncated moment of certain function of the 1st order statistic.
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Introduction NAA (N-acetyl-aspartate) is the second most abundant molecule in the CNS (after glutamate), its MRS signal is commonly used as a putative marker of viable neurones, and yet little is known about its function. Furthermore, recent data from cell culture has raised the possibility of an additional cellular contribution of NAA from nonneuronal origins, principally in isolated mature ol...
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چکیده ندارد.
15 صفحه اولA modified Weibull distribution
A new lifetime distribution capable of modeling a bathtub-shaped hazard-rate function is proposed. The proposed model is derived as a limiting case of the Beta Integrated Model and has both the Weibull distribution and Type I extreme value distribution as special cases. The model can be considered as another useful 3-parameter generalization of the Weibull distribution. An advantage of the mode...
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ژورنال
عنوان ژورنال: Molecular Genetics and Metabolism
سال: 2014
ISSN: 1096-7192
DOI: 10.1016/j.ymgme.2014.07.002